When I first started testing vSphere 5 in my home lab, I began from scratch. One of the steps that was relatively familiar was binding VMKernal adapters to the physical NICs for iSCSI use.
If you have NICs that have iSCSI offload capabilities without having to use the Software iSCSI Adapter, then you are used to using a command similar to this:
esxcli swiscsi nic add -n vmk2 -d vmhba34
You can watch more on it here How to configure iSCSI Port Binding on vSphere 4
This has been cleaned up a bit in vSphere 5, further taking you away from using the cli and putting this capability in the GUI. It's a nice addition and just a little nugget that just might interest you.
I also like how it incorporates the Port Group Policy. The port group policy is the same as it was in vSphere 4 by making sure the NICs you are using for iSCSI are the only ones in use to correctly configure multipathing.
